• Plant Biotechonology Laboratory


• Plant Genomics Research Laboratory


• Plant Pathology Laboratory


• GMO Laboratory


• Yeast Biotechnology and Genomics Research Lab


• Proteomics Laboratory


• Plant Chemistry Laboratory


• Molecular Diagnosis in Human Diseases lab


• Animal Tissue Culture Laboratory

Clonal produciton/propagation of various plants like corns, medicinal plants, forest trees by tissue culture technique. Detection of tolerance to abiotic stress conditions as salt, drought, pressure by molecular and fenotipic tests. Gene transfer to plants.

Researches:

Micropropagation of ornamentals and forest trees that are used for landscaping.

1. Detection of tolerance to abiotic stress conditions as salt, drought, pressure  by molecular and fenotipic tests.
2. Epigenetic analyses
3. Gen transfer devoted to plant improvement.
4. Scientific consultancy and education services

30, 45, 60 day barley (Hordeum vulgare L.) callus - plant production in tissue culture

Analyses of motilities in plant genome on chromosomal and transposonal level. Structural and functional analysis of genes important for biotechnology.  

Researches:

1. Extraction of macromolecules (DNA, RNA, protein) from plants.
2. Genotyping of accessions with molecular markers.
3. Functional analysis of specific genes by real-time PCR
4. Scientific advisory and education on plant genomics, gene transfer and cloning methods

BARE-1 transposon analysis by IRAP method  in Barley  (Hordeum vulgare L.) callus

Molecular diagnosis of bacterial and fungal pathogens (Pseudomonas, Fusarium) causing diseases in economically important crops. Chemotyping studies in fungal species for determination of their specifically produced toxins.

Researches:

1. Diagnosis of Fusarium head blight and root/rot diseases in cereals
2. Chemotyping of Fusarium spp. Strains for their mycotoxin production.
3. Molecular diagnosis of Pseudomonas syringe pathovars.
4. Scientific advisory and education on plant pathology

Production and genotyping of Fusarium culmorum

Detection of GMO or detection of manipulations for gene expression change in plants and products

Researches:

1. GMO analysis in processed (biscuits, potato chip, tomato paste etc. ) and non-processed (seed, fruit, stem, root etc.) products.
2. Scientific advisory and education
   

Relationship between magnesium transportation and mitotic microtubules formation in Schizosaccharomyces pombe, gene expression profiling of copper induced responses  in the fission yeast, molecular mechanisms of glucose repression, production of biotechnologically  important products through recombinant DNA technology in large quantities in yeast and using yeast cells as a model organism for determining the objectives and activities new molecules

Researches:

1. Fundamental Yeast Genetics applications
2. Macromolecule (DNA, RNA, protein) isolation from yeasts.
3. Developing of Industrial microorganism using mutagenesis and recombinant DNA technology
4. Production of biotechnological products in large quantities in yeast
5. Heterolog gene expression in yeasts
6. Scientific counseling and education service on yeast molecular biology.

Fluoresan microscopy image of "Calcofluor" stained Scizosaccharomyces pombe cells

Yeast specific cell counting machine

Researches on stress proteins and protein oxidation by proteomic techniques, detection of macromolecular (DNA, protein, lipid) damages resulted from oxidative stress, elucidation of antioxidation and detoxification mechanisms in living cells and antioxidant, antifungal and antibacterial activities of natural products.

Researches:

1. Detection of macromolecular (DNA, protein, lipid) damages
2. Protein analyses
3. Enzyme activity tests
4. Antioxidant activity tests
5. Scientific consultancy and education services

2-D gel electrophoresis image

Western blotting analyses of 14-3-3 proteins

Isolation and purification of bioactive compounds from plants.

Araştırmalar:

1. Essential (volatile) oil analyses
2. Fixed oil analyses
3. Determination of photo-stimulative characteristics
4. Scientific consultancy and education services

Determination of molecular markers and identification of genetic factors playing a rol in the etiology of various autoimmune and infectious disease. Investigation of genetic diseases from prenatal diagnosis by molecular techniques

Researches:

1. Determination of various otoimmune disease as Romatoid artrid, skleroderma, Behçet's disease and infectious diseases as tuberculosis, lepra on molecular level.
2. Molecular genetic analyses for diagnosis and treatment of genetically origined diseases .
3. Determination of genetic variations responsible from various diseases in Turkish population.
4. Determination of the baby's blood group from Amniotic fluid
5.  Diagnosis of the sex-related diseases from  Amniotic fluid.
6. Determination  of the presence of RHD gene of infants in the mother blood
7. Epigenetic analyses with twins
8. Scientific consultancy and education services

Real-time PCR machine in molecular diagnosis laboratory and a brochure of RhD diagnosis

In vitro studies on the mechanism of some human diseases as well as action mechanism of natural bioactive substances

Researches:

1. Cytotoxicity analyses
2. Antiviral activity tests
Determination of intracellular oxidation level

C6 glioma cell line