CIRRUCILUM VITAE

ÖZDEN HATIRNAZ
ozdenhatirnaz@students.istanbul.edu.tr

Personal info

·Place and Date of Birth : İstanbul, 08. 31. 1979
·Gender : Female
· Martial Status : Single

Foreign Language

· English : Advanced

Educational Background

·2002- ongoing Institute of Experimental Medicine,Department of Genetics,Istanbul Universty,Istanbul, Turkey (MsC)
· 1998- 2002 : Faculty of Sciences, Department of
Biology, Istanbul Universty,
Istanbul, Turkey (Undergraduate)
· 1994-1997 : Hayrullah Kefoglu High School
Istanbul, Turkey
· 1990-1994 : Private Eyuboglu High School
Istanbul, Turkey

Internship
8-22 September 2003 : University of Heidelberg
Institute For Human Genetics,
MRD Laboratory, Heidelberg, Germany (Dr. Bartram-Dr. Flohr)

July 2002-September 2002 : St.Jude Children’s Research Hospital,Department of Pharmaceutical Sciences,Memphis,USA (Dr. Relling)

June 2000 –July2002 : Institute of Experimental Medicine Research, Department of Genetics, Istanbul University Istanbul,Turkey
(Dr. Özbek)

Projects Participated

·Detection of Minimal Residual Disease in Adult ALL Patients with Ig/TCR rearrangements

· Expression analysis of BAD, BAX, FLI1and CXCR4 genes in t(12;21) positive patients with Realtime-Quantitative PCR

· HFE gene mutation frequencies in Chronic Liver Patients.

·Allele frequencies of TPMT *2, *3A, *3B and *3C in Turkish population.

· CYP1A1, CYP2D6, CYP2E1, GSTT1 & GSTM1 Gene Polymorphisms
and their role in Acute Leukemia Ethiology

Abstracts:
· M. C. Ar, S. Sirma, O. Hatirnaz, Ş. Öngören, Ü. Üre, Z. Başlar, Y. Aydın, B. Ferhanoglu, U. Özbek. Detection of Minimal Residual Disease in Adult ALL Patients with Ig/TCR rearrangements. XXX. National Haematology Congres, 10-14 October 2003, Istanbul, Turkey. (Oral Presentation)

· H. Savli, S. Sirma, O. Hatirnaz, U. Özbek. Expression analysisi of apoptotic BAD and BAX genes in t(12;21) positive ALL patients with Real Time-Quantitative PCR XXX. National Haematology Congres, 10-14 October 2003, Istanbul, Turkey. (oral Presentation)

· M.A. Sayitoglu, O. Hatirnaz, U. Özbek. The role of detoxification enzymes in ethiology of Acute Leukemias. XXX. National Haematology Congres, 10-14 October 2003, Istanbul, Turkey. (Oral Presentation)

· Ş. Palandüz, A. Bayrak, S. Sirma, Ö. Hatirnaz, M. Aktan, S. Yavuz, S. K. Beşışık, G. Dinçol, U. Özbek. The Cytogenetic and Molecular Response to Imanitib Mesylate in CML patients. XXX. National Haematology Congres, 10-14 October 2003, Istanbul, Turkey. (Poster Presentation)

· O. Hatirnaz, H. Savli, S. Sirma, U. Özbek. The expression analysis of CXCR4 and FLI1 genes in t(12;21) positive ALL patients. XXX. National Haematology Congres, 10-14 October 2003, Istanbul, Turkey. (Poster Presentation)

·M.Aydin, O.Hatirnaz, S.Sirma,S.Anak, I.Yildiz, L.Agaoglu, L .Yuksel, O.Devecioglu, H.Apak, N. Yalman, T. Celkan, G. Gedikoglu, A. Kandilci, U.Ozbek
Glutathione S-Transferase T1 and M1 polymorphisms: Susceptibility to childhood acute lymphoblastic leukemia (ALL);Cancer 2002,An international Symposium,14-16 October 2002 Riyadh, Kingdom Of Saudi Arabia (Oral Presantation)

· M.Aydin, O.Hatirnaz ,U.Ozbek Allelotype frequencies of TPMT ,CYP 3A4 and CYP3A5 genes in Turkish Population December 6-10 2002 Philadelphia,Pennsylvania (Poster Presentation)

· M.Aydin, O.Hatirnaz, S.Anak, I.Yildiz, L.Agaoglu, L .Yuksel, O.Devecioglu, A. Unuvar, Z. Karakas, Z. Salcioglu, Ç. Timur, H.Apak, U.Ozbek
GSTM1,CYP2E1 and CYP1A1 are found to be risk factors in ethiology of acute leukemia. XXIX. National Hematology Congres; October 25-28 2002, Kemer,Antalya (Oral Presentation)

·U.Ozbek, M.Aydin, O.Hatirnaz, L. Agaoglu, S.Sirma, L.Yuksel, S.Anak, H.Apak, Z.Karakas, T.Celkan, O.Devecioglu, A.Ozkan, G.Gedikoglu, İ.Yildiz (Intr.By
M.Aktan) Metabolising enzyme polumorphisms (GSTM1, GSTT1, CYP1A1, CYP2D6) and their association as a potential susceptibility to pediartic ALL. American Society of Hematology 43rd Annual Meeting and Exposition; December 7-11, 2001 Orlando, FL (Oral Presentation)

·M.Aydin, O.Hatirnaz, S.Sirma,S.Anak, I.Yildiz, L.Agaoglu, L .Yuksel, O.Devecioglu, H.Apak, U.Ozbek
Glutathione S-Transferase T1 and M1 polymorphisms: Susceptibility to childhood acute lymphoblastic leukemia (ALL); The Second Eurapean-American Intensive Course in Clinical and Forensic Genetics ; September 3-14 2001 , Dubrovnik, Croatia (Poster Presentation)

·M.Aydin, O.Hatirnaz, S.Sırma, S.Anak, L.Yuksel, L.Agaoglu, I.Yildiz, O.Devecioglu, H.Akpak, U. Ozbek
GSTM1, GSTT1, CYP2D6, CYP1A1 gen polymorphisms and their role in pediatric ALL ethiology; The third national pediatric hematology congres; October 17-20 2001, Ankara, Turkey (Poster Presentation)

Awards:
· O. Hatirnaz, H. Savli, S. Sirma, U. Özbek. The expression analysis of CXCR4 and FLI1 genes in t(12;21) positive ALL patients. XXX. National Haematology Congres, 10-14 October 2003, Istanbul, Turkey. Young Participant Award

· M. C. Ar, S. Sirma, O. Hatirnaz, Ş. Öngören, Ü. Üre, Z. Başlar, Y. Aydın, B. Ferhanoglu, U. Özbek. Detection of Minimal Residual Disease in Adult ALL Patients with Ig/TCR rearrangements. XXX. National Haematology Congres, 10-14 October 2003, Istanbul, Turkey. Turkish Society of Haematology Declaration Award

· M.Aydin, O.Hatirnaz, S.Anak, I.Yildiz, L.Agaoglu, L .Yuksel, O.Devecioglu, A. Unuvar, Z. Karakas, Z. Salcioglu, C. Timur, H.Apak, U.Ozbek
GSTM1,CYP2E1 and CYP2A1 gene polymorphisms are found to be risk factors in acute leukemia ethiology. XXIX National Haematology Congres October 25-28 2002 Kemer,Antalya Pharmacia Special Award